| Value |
0.3
unitless
|
| Organism |
Mammals |
| Reference |
Saari JC. Biochemistry of visual pigment regeneration: the Friedenwald lecture. Invest Ophthalmol Vis Sci. 2000 Feb41(2):337-48. p.341 right column bottom paragraphPubMed ID10670460
|
| Primary Source |
Matchinsky FM. Quantitative histochemistry of nicotinamide adenine nucleotides in retina of monkey and rabbit. J Neurochem. 1968 15: 643–657.PubMed ID4386358
|
| Method |
Quantitative histochemistry |
| Comments |
"Studies of glucose metabolism emphasized that
ROSs [rod outer segments] were capable of producing NADPH through the pentose
phosphate pathway in amounts sufficient to account for reduction
of all-trans-retinal.[ref 54] However, in dark-adapted rabbit and
monkey retina, the ratio of NADPH to nicotinamide adenine
dinucleotide phosphate (NADP) was reported to be 0.3, [primary source]
indicating that the pathway would have to be activated for reduction to occur. In vivo [13C] nuclear magnetic resonance
studies of rabbit retina have demonstrated an activation of the
pentose phosphate pathway in constant light.[ref 56]" |
| Entered by |
Uri M |
| ID |
111398 |