Range |
~1,400 µm^3
|
Organism |
Human Homo sapiens |
Reference |
Wisniewski JR, Ostasiewicz P, Dus K, Zielinska DF, Gnad F, Mann M. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma. Mol Syst Biol. 2012 8: 611. doi: 10.1038/msb.2012.44. p.8 right column 2nd paragraphPubMed ID22968445
|
Primary Source |
Buschmann RJ, Manke DJ (1981) Morphometric analysis of the membranes and organelles of small intestinal enterocytes. I. Fasted Hamster. J Ultrastruct Res 76: 1–14 & MacLeod et al., (1991) Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes. Proc Natl Acad Sci USA 88: 552–556 & Crowe PT, MarshMN(1993) Morphometric analysis of small intestinal mucosa. IV. Determining cell volumes. Virchows Arch A Pathol Anat Histopathol 422: 459–466PubMed ID7277572, 1703302, 8333150
|
Comments |
"To calculate copy numbers of proteins in the enterocytes, [researchers]
assumed the volume of these cells to be about 1400µm^3
(primary sources) and the protein content of mammalian cells
to be about 20% (BNID 111217)." |
Entered by |
Uri M |
ID |
111216 |