Average actin filament length
| Range | in isolated actin patches 50nm: in patches on plasma membranes 100nm nm |
|---|---|
| Organism | Yeast |
| Reference | Berro J, Sirotkin V, Pollard TD. Mathematical modeling of endocytic actin patch kinetics in fission yeast: disassembly requires release of actin filament fragments. Mol Biol Cell. 2010 Aug 15 21(16):2905-15. doi: 10.1091/mbc.E10-06-0494. p.2910 right column bottom paragraphPubMed ID20587776 |
| Primary Source | [1] Young, M. E., Cooper, J. A., and Bridgman, P. C. (2004). Yeast actin patches are networks of branched actin filaments. J. Cell Biol. 166, 629–635. [2] Rodal, A. A., Kozubowski, L., Goode, B. L., Drubin, D. G., and Hartwig, J. H. (2005). Actin and septin ultrastructures at the budding yeast cell cortex. Mol. Biol. Cell 16, 372–384.PubMed ID15337772, 15525671 |
| Comments | "Capping at the rate observed in cells terminated elongation in ~0.2 s when the average filament was only a couple hundred of nanometers long. The ratios of polymerized actin to the number of filament ends in [researchers'] simulations gave a similar estimate of 100–150 nm (Figure 3D), a length that varied little during patch assembly and disassembly. Filament lengths estimated by these simulations are similar to average lengths observed by electron microscopy of budding yeast patches: 50 nm (corresponding to ~19 subunits) in isolated actin patches (primary source [1]) and 100 nm (38 subunits) in patches on plasma membranes (primary source [2])." |
| Entered by | Uri M |
| ID | 111093 |