| Value |
1E-10
cm/sec
|
| Organism |
Human Homo sapiens |
| Reference |
Wood RE, Wirth FP Jr, Morgan HE. Glucose permeability of lipid bilayer membranes. Biochim Biophys Acta. 1968 Sep 17 163(2):171-8. Abstract, see revised value in p.176 top paragraphPubMed ID5686274
|
| Method |
"Bimolecular lipid membranes have been prepared from total phospholipid
extracts of human red cells. The electrical properties and water permeability of these
membranes were similar to values reported earlier for other bilayer membranes." |
| Comments |
"The upper limit of the glucose permeability coefficient was estimated to be 10X10^-8 cm/sec, (some 10^6-fold lower than that of the human red cell.) These observations suggest that sugar transport involves membrane constituents other than lipids. The lipid bilayer model may prove to be a useful tool for the isolation and characterization of membrane proteins that may function as carriers...[revised value, p.176 top paragraph:] These data suggest that the
permeability coefficient for glucose must be revised downward by at least two orders
of magnitude. The upper limit of glucose permeability would appear to be 10^-10cm/sec." |
| Entered by |
Uri M |
| ID |
110830 |