| Range |
oxidative phosphorylation ~80%: aerobic glycolysis ~20% %
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Fan J, Kamphorst JJ, Mathew R, Chung MK, White E, Shlomi T, Rabinowitz JD. Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol Syst Biol. 2013 Dec 3 9: 712. doi: 10.1038/msb.2013.65. p.3 left columnPubMed ID24301801
|
| Method |
"To study ATP production routes, [researchers] used Bax-/-, Bak-/-
murine renal epithelial cells immortalized by expression of
adenovirus E1A and dominant-negative p53 (Degenhardt et al,
2002) (iBMK cells)." |
| Comments |
"The total ATP production rate in the parental iBMK cell line
was found to be 861 nmole/µl cells/h (where µl refers to the
packed cell volume, with 1µl equal to ~10^6 cells). The relative
contribution of oxidative phosphorylation and aerobic glycolysis was ~80 and 20%, respectively (Supplementary Table 3 BNID 110689), consistent with previous results (Zu and Guppy, 2004, PMID 14697210)." iBMK=Immortalized baby mouse kidney epithelial cells |
| Entered by |
Uri M |
| ID |
110684 |