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Fraction of lung cancers in which a mutation in p53 is found

Range	>50 %
Organism	Human Homo sapiens
Reference	Cairns J. Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. Proc Natl Acad Sci U S A. 2002 Aug 6 99(16):10567-70. p.10569 right column 2nd paragraphPubMed ID12149477
Primary Source	[14] Hainaut, P. & Pfeiffer, G. P. (2001) Patterns of p53 G>T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke., Carcinogenesis 22, 367 – 374PubMed ID11238174
Comments	P.10569 right column 2nd paragraph: "Mutations in p53 are found in more than 50% of lung cancers (primary source)."
Entered by	Uri M
ID	110653