Percent of of total brain ATP consumption that is accounted for by Glutamate-generated electrical activity

Range ~80 %
Organism Rodent
Reference Bernstein BW, Bamburg JR. Actin-ATP hydrolysis is a major energy drain for neurons. J Neurosci. 2003 Jan 1 23(1):1-6. p.1 left column top paragraphPubMed ID12514193
Primary Source Attwell D, Laughlin SB (2001) An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab 21: 1133–1145.PubMed ID11598490
Comments "Glutamate-generated electrical activity alone accounts for ~80% of total brain ATP consumption (primary source). This large energy consumption is assumed to be needed for restoring transmembrane ionic gradients via pumps."
Entered by Uri M
ID 110637