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Average half-time (t1/2) of GroEL-assisted protein folding

Range	60 sec
Organism	Bacteria Escherichia coli
Reference	Kerner MJ, Naylor DJ, Ishihama Y, Maier T, Chang HC, Stines AP, Georgopoulos C, Frishman D, Hayer-Hartl M, Mann M, Hartl FU. Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli. Cell. 2005 Jul 29 122(2):209-20. p.214 right columnPubMed ID16051146
Primary Source	Ewalt KL, Hendrick JP, Houry WA, Hartl FU. In vivo observation of polypeptide flux through the bacterial chaperonin system. Cell. 1997 Aug 8 90(3):491-500.PubMed ID9267029
Comments	P.214 right column: "More than 3% of a protein is expected to be GroEL associated when all folding must proceed via GroEL (assuming a doubling time of E. coli of 30–40 min and an average half-time (t1/2) of GroEL-assisted folding of ∼60 s see primary source)."
Entered by	Uri M
ID	110580