Energy cost without core metabolic energy
Range | 68mmolATP/gDW (equal to ~12*10^9 ATP/cell) |
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Organism | Bacteria Escherichia coli |
Reference | Feist AM, Henry CS, Reed JL, Krummenacker M, Joyce AR, Karp PD, Broadbelt LJ, Hatzimanikatis V, Palsson BØ. A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information. Mol Syst Biol. 2007 3:121. doi:10.1038/msb4100155 p.7 right column 2nd paragraph, p.10 right column bottom paragraph, p.15 left column 7th paragraph & right column 2nd paragraph (converted to ATP/cell by Ron Milo, see comments section) |
Comments | 68mmolATP/gDW is sum of BNID 110421, 110422 "68*10^-3 mol ATP/g cell * 6*10^23 ATP molecules/mol ATP * 0.3*10^-12 g cell/cell ~ 120*10^(-3+23-12) =1.2*10^10 or 12 billion ATP/cell. I used 0.3*10^-12 g/cell as this is a good value for the dry cell weight at a 40 min doubling time." |
Entered by | Uri M |
ID | 110423 |