| Range |
lateral bond energy -2.2 to -5.7kT longitudinal bond energy -6.8 to -9.4kT kT
|
| Organism |
Eukaryotes |
| Reference |
Tuszynski JA, Luchko T, Portet S, Dixon JM. Anisotropic elastic properties of microtubules. Eur Phys J E Soft Matter. 2005 May17(1):29-35. p.31 left column 2nd paragraphPubMed ID15864724
|
| Primary Source |
VanBuren V, Odde DJ, Cassimeris L. Estimates of lateral and longitudinal bond energies within the microtubule lattice. Proc Natl Acad Sci U S A. 2002 Apr 30 99(9):6035-40.PubMed ID11983898
|
| Method |
(Primary source abstract:) "[Researchers] developed a stochastic model of microtubule (MT) assembly dynamics that estimates tubulin-tubulin bond energies, mechanical energy stored in the lattice dimers, and the size of the tubulin-GTP cap at MT tips." |
| Comments |
"In fact, a recent paper by VanBuren et al. [primary source] estimated the values of lateral and longitudinal bond energies
in an MT (microtubule) structure using a stochastic model of assembly
dynamics. Their analysis predicts the lateral bond energy
to be in the range from -2.2 to -5.7kT (which translates
to -9.1?10^-21 to -2.4?10^-20J) while the longitudinal
bond energy is given from -6.8 to -9.4kT (-2.8?10^-20
to -3.9?10^-20J)." |
| Entered by |
Uri M |
| ID |
110107 |