Predicted myosin II-generated radial stresses

Range ~0.05 nN/μm^2
Organism Amoeba Dictyostelium discoideum
Reference D.N. Robinson, Y.-S. Kee, T. Luo and A. Surcel, Understanding How Dividing Cells Change Shape. In: Edward H. Egelman, editor: Comprehensive Biophysics, Vol 7, Cell Biophysics, Denis Wirtz. Oxford: Academic Press, 2012. pp. 48-72. p.57 right column 2nd paragraph
Primary Source Robinson, D. N. Cavet, G. Warrick, H. M. Spudich, J. A. Quantitation of the distribution and flux of myosin-II during cytokinesis. BMC Cell Biol. 2002, 3, 4. AND Zhang, W. Robinson, D. N. Balance of actively generated contractile and resistive forces controls cytokinesis dynamics. Proc. Natl. Acad. Sci. USA 2005, 102, 7186–7191.PubMed ID11860600, 15870188
Method "...from the total amount of myosin II (~100,000 hexamers), force/head (3 pN), unloaded duty ratio (0.6%), and the surface area of the cleavage furrow (75µm^2), the predicted myosin II-generated radial stresses are estimated to be ~0.05nN/µm^2 and a total force of ~4nN (primary sources)."
Entered by Uri M
ID 109571