| Range |
Table - link µM
|
| Organism |
African clawed frog Xenopus laevis |
| Reference |
Uchino H et al., Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Mol Pharmacol. 2002 Apr61(4):729-37. p.732 table 1PubMed ID11901210
|
| Method |
"To understand the mechanisms of substrate recognition,
[researchers] have examined the LAT1-mediated transport using a Xenopus
laevis oocyte expression system." |
| Comments |
"...amino acids with bulky side chains are competitive
inhibitors of LAT1-mediated transport with Ki values comparable
with those of L-dopa and other phenylalanine derivatives
(Table 1)." |
| Entered by |
Uri M |
| ID |
109027 |