Zinc sensitivity of the SmtB protein
| Range | <0.01 nM to 3.5 mM |
|---|---|
| Organism | Cyanobacteria Synechococcus elongatus PCC 7942 |
| Reference | Outten CE, O'Halloran TV. Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis. Science. 2001 Jun 29 292(5526):2488-92. p.2488 middle column 2nd paragraphPubMed ID11397910 |
| Primary Source | Kar SR, Adams AC, Lebowitz J, Taylor KB, Hall LM. The cyanobacterial repressor SmtB is predominantly a dimer and binds two Zn2+ ions per subunit. Biochemistry. 1997 Dec 9 36(49):15343-8. AND VanZile ML, Cosper NJ, Scott RA, Giedroc DP. The zinc metalloregulatory protein Synechococcus PCC7942 SmtB binds a single zinc ion per monomer with high affinity in a tetrahedral coordination geometry. Biochemistry. 2000 Sep 26 39(38):11818-29.PubMed ID9398263, 10995250 |
| Comments | "Estimates of the zinc sensitivity of the Synechococcus PCC7942 SmtB protein vary from <0.01 nM to 3.5 mM(primary sources)" |
| Entered by | Uri M |
| ID | 108828 |