Fraction of proteins encoded by the genome that require zinc for their function

Value 10 %
Organism Human Homo sapiens
Reference Simm C et al., Saccharomyces cerevisiae vacuole in zinc storage and intracellular zinc distribution. Eukaryot Cell. 2007 Jul6(7):1166-77. p.1166 left column top paragraphPubMed ID17526722
Primary Source Andreini, C., L. Banci, I. Bertini, and A. Rosato. 2006. Counting the zinc-proteins encoded in the human genome. J. Proteome Res. 5: 196-201.PubMed ID16396512
Comments p.1166 left column top paragraph:"Zinc is an important structural and/or catalytic cofactor for numerous proteins. For example, it was estimated recently that as many as 10% of the approximately 30,000 different proteins encoded by the human genome require zinc for their function (primary source)."
Entered by Uri M
ID 111629