| Value |
12000
Ca2+/vesicle released
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001 Oct21(10):1133-45. p.1136 left column 3rd paragraphPubMed ID11598490
|
| Primary Source |
Helmchen F, Borst JG, Sakmann B. Calcium dynamics associated with a single action potential in a CNS presynaptic terminal. Biophys J. 1997 Mar72(3):1458-71.PubMed ID9138591
|
| Comments |
"The presynaptic action potential triggers an influx of 1.2×10^4 Ca2+ per vesicle released (at 35°C at calyx synapses
(primary source)). This will be extruded by 3 Na+/Ca2+
exchange, requiring 1.2×10^4 ATPs." |
| Entered by |
Uri M |
| ID |
108626 |