Biopolymer mass density in the model cytoplasm

Range 250 to 350 mg/ml
Organism Bacteria Escherichia coli
Reference Bakshi S, Siryaporn A, Goulian M, Weisshaar JC. Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol Microbiol. 2012 Jul85(1):21-38. doi: 10.1111/j.1365-2958.2012.08081.x. p.33 left column 2nd paragraphPubMed ID22624875
Primary Source Ando T, Skolnick J. Crowding and hydrodynamic interactions likely dominate in vivo macromolecular motion. Proc Natl Acad Sci U S A. 2010 Oct 26 107(43):18457-62PubMed ID20937902
Comments "...estimates enable rough comparison of [researchers'] results to a recent model diffusion calculation treating cytoplasmic elements as appropriately sized hard spheres and including hydrodynamic interactions (primary source). The biopolymer mass density in the model cytoplasm varied from 250 to 350 mg ml-1, with the mole fraction of each component (proteins and ribosomes) derived from content measurements and kept constant."
Entered by Uri M
ID 108607