| Value |
160
multimeric complexes/cell
|
| Organism |
Bacteria Mycoplasma pneumoniae |
| Reference |
Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol Syst Biol. 2011 Jul 19 7: 511. doi: 10.1038/msb.2011.38. p.5 right column bottom paragraphPubMed ID21772259
|
| Method |
Mass spectrometry and Western blot validation: "...researchers measured individual protein levels in average copies per cell
under control conditions (growth for 96 h), along a 4-day time
course, in response to heat shock, DNA damage and osmotic
stress (Supplementary Table S2)." |
| Comments |
"For several well-characterized protein complexes, such as
the GroEL/ES chaperonin (160 multimeric complexes per
cell), DNA gyrase (50 A2B2 tetramers per cell) or ribonucleoside-
diphosphate reductase (300 copies per cell), cellular
abundances of the subunits reflect the expected complex
stoichiometries closely (Figure 4B Supplementary Figure S13)." |
| Entered by |
Uri M |
| ID |
108351 |