Mutation rate in individual whose sperm was sequenced

Range 2e-8 to 4e-8 Mutations/site/generation
Organism Human Homo sapiens
Reference Jianbin Wang, H. Christina Fan, Barry Behr and Stephen R. Quake Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm, Cell 150, 402–412, July 20, 2012 p.408 right column bottom paragraphPubMed ID22817899
Method P.403 left column 2nd paragraph: "[Researchers] collected a sperm sample from a 40-year-old Caucasian individual (P0) whose genome has been sequenced (Pushkarev et al., 2009), clinically annotated (Ashley et al., 2010), and haplotype phased (Fan et al., 2011)."
Comments P.408 right column bottom paragraph: "P0’s mutation rate (2–4×10^-8) is higher than that obtained from genome-sequenced pedigree data (~1×10^-8) (Conrad et al., 2011), but it is consistent with evolutionary studies, which have revealed ~4–5× more mutations in male than in female, possibly due to the larger number of germline cell divisions in male (Crow, 2000 Makova and Li, 2002)."
Entered by Uri M
ID 108040