|Ingolia NT. Genome-wide translational profiling by ribosome footprinting. Methods Enzymol. 2010 470:119-42. p.122 fig.6.1PubMed ID20946809
|Ribosome footprints are generated by nuclease digestion of polysomes in cell extracts. Nuclease treatment degrades the mRNA that links together polysomes, freeing individual ribosomes (fig 6.1)
|Ribosomes protect 28 nt mRNA footprint from nuclease digestion.