| Range |
500 to 700 nts/sec
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Yao NY, Georgescu RE, Finkelstein J, O'Donnell ME. Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression. Proc Natl Acad Sci U S A. 2009 Aug 11 106(32):13236-41 p.13236 right column top paragraphPubMed ID19666586
|
| Primary Source |
Mok M, Marians KJ. The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate. J Biol Chem. 1987 Dec 5 262(34):16644-54. AND McInerney P, Johnson A, Katz F, O'Donnell M. Characterization of a triple DNA polymerase replisome. Mol Cell. 2007 Aug 17 27(4):527-38.PubMed ID2824502, 17707226
|
| Comments |
Processivity estimates of the E. coli replisome from ensemble
studies indicate a lower limit of 50 kb, and an average bulk rate
of ~500–700 nt/s at 37 °C (primary sources). |
| Entered by |
Uri M |
| ID |
107691 |