Range of single-channel conductances of amiloride-sensitive Na+ channels of U937 cells
| Range | 3 to 40 pS |
|---|---|
| Organism | Human Homo sapiens |
| Reference | Gamper N, Huber SM, Badawi K, Lang F. Cell volume-sensitive sodium channels upregulated by glucocorticoids in U937 macrophages. Pflugers Arch. 2000 Dec441(2-3):281-6. p.285 right column bottom paragraphPubMed ID11211114 |
| Comments | pS=picoSiemens. U937=human histiocytic lymphoma cells. Amiloride-sensitive Na+ channels form a wide superfamily of channels with single-channel conductances in the range of 3–40 pS, Na+ over K+ selectivity of between 1 and 50, and an IC50 for amiloride-induced inhibition in the range of 0.1–10 µM (see PMID 9114818 for review). |
| Entered by | Uri M |
| ID | 107639 |