Average number of side chains that are part of the active site pocket
| Value | 34 Amino acids/pocket Range: ±0.77 Amino acids/pocket |
|---|---|
| Organism | Generic |
| Reference | Jimenez-Morales D, Liang J, Eisenberg B. Ionizable side chains at catalytic active sites of enzymes. Eur Biophys J. 2012 Apr 7. p.11 2nd paragraphPubMed ID22484856 |
| Method | Researchers use the Molecular Surface (MS) model (Connolly 1985) in CASTp to determine metrics—e.g., the volume—of all pockets. |
| Comments | For 2 definitions of the (catalytic) active site pocket see p.5 4th paragraph |
| Entered by | Uri M |
| ID | 107579 |