| Range |
Table - link
|
| Organism |
African clawed frog Xenopus laevis |
| Reference |
Kubick C, Schmalzing G, Markwardt F. The effect of anions on the human P2X7 receptor. Biochim Biophys Acta. 2011 Dec1808(12):2913-22 p.2916 table 1PubMed ID21872569
|
| Method |
Researchers examined the
effects of anions on the function of the hP2X7R, which was
heterologously expressed in Xenopus laevis oocytes. By using the
voltage-clamp technique, membrane potential-dependent effects
could be excluded. |
| Comments |
P2X7 receptors (P2X7Rs) are nonselective cation channels that are opened by the binding of extracellular ATP and are involved in the modulation of epithelial secretion, inflammation and nociception. pKD1 and pKD2 are the negative decadic logarithms of the apparent
ATP dissociation constants. |
| Entered by |
Uri M |
| ID |
107334 |