| Value |
76
M^-1×sec^-1
|
| Organism |
Generic |
| Reference |
Woodmansee AN, Imlay JA. Reduced flavins promote oxidative DNA damage in non-respiring Escherichia coli by delivering electrons to intracellular free iron. J Biol Chem. 2002 Sep 13 277(37):34055-66 p.34056 left column top paragraphPubMed ID12080063
|
| Primary Source |
Walling, C. Fenton's reagent revisited (1975) Acc. Chem. Res. 8, 125–131 |
| Comments |
P.34056 left column top paragraph: "In fact, the efficiency with which exogenous H2O2 damages DNA provides evidence that iron re-reduction must be rapid. When Escherichia coli is treated with 2.5 mM H2O2, DNA damage is generated at a high rate for up to 20 min (ref 13). At this concentration of H2O2 the Fenton reaction (76 M^-1×s^-1 (primary source)) should oxidize pre-existing reduced iron within seconds-the observation that damage occurs steadily indicates that a reductant recycles the iron very
efficiently." |
| Entered by |
Uri M |
| ID |
105678 |