Rate constant for OH- attack of an acetylcholine in water

Value 2.2 M^-1×sec^-1
Organism Unspecified
Reference Monika Fuxreiter and Arieh Warshel, Origin of the Catalytic Power of Acetylcholinesterase:? Computer Simulation Studies, J. Am. Chem. Soc., 1998, 120 (1), pp 183–194 DOI: 10.1021/ja972326m p.184 left column bottom paragraph
Primary Source Wright, M. R. J. Chem. Soc. B 1968, 545.
Comments "...the rate in [AChE] enzyme is around 10^8M^-1×sec^-1 while the rate constant for OH- attack an acetylcholine in water is 2.2M^-1×sec^-1. (primary source)"
Entered by Uri M
ID 109217