| Range |
Table - link
|
| Organism |
Bacteria Staphylococcus aureus |
| Reference |
Chung P, McNamara PJ, Campion JJ, Evans ME. Mechanism-based pharmacodynamic models of fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 2006 Sep50(9):2957-65. free online article p. 2961 table 2PubMed ID16940088
|
| Method |
Researchers developed two novel pharmacodynamic models that assign
mechanisms of action to fluoroquinolone antimicrobial
agents (growth inhibition or death stimulation) and compared
the abilities of these models and two other maximum effect
models—our previously described net effect model (ref 5 in article) and the
MIC-based model reported by Meagher and colleagues
(ref 18 in article) to describe and predict the changes in bacterial population
dynamics during in vitro system experiments where S.
aureus was exposed to a series of simulated ciprofloxacin pharmacokinetic
profiles (refs 4,5 in article). |
| Comments |
See BNID 101559 |
| Entered by |
Uri M |
| ID |
105553 |