| Range |
30-70 nucleotides
|
| Organism |
Unspecified |
| Reference |
Rimmele M. Nucleic acid aptamers as tools and drugs: recent developments. Chembiochem. 2003 Oct 6 4(10):963-71.PubMed ID14523912
|
| Method |
Systematic Evolution of Ligands by EXponential enrichment (SELEX). SELEX comprises an iterative process of
in vitro selections of nucleic-acid target-binding events
and partitioning events of unbound nucleic acids and is
used to isolate high-affinity nucleic acid ligands from
large pools of randomized nucleic acid sequence
libraries. |
| Comments |
Nucleic acid aptamers are molecules that bind to their ligands with
high affinity and specificity. Unlike other functional nucleic acids
such as antisense oligonucleotides, ribozymes, or siRNAs, aptamers
almost never exert their effects on the genetic level. |
| Entered by |
Uri M |
| ID |
105440 |