| Range |
Table - link
|
| Organism |
Unspecified |
| Reference |
Mairal T, Ozalp VC, Lozano Sánchez P, Mir M, Katakis I, O'Sullivan CK. Aptamers: molecular tools for analytical applications. Anal Bioanal Chem. 2008 Feb390(4):989-1007.PubMed ID17581746
|
| Primary Source |
Pointers to refs in table |
| Method |
FRET (fluorescence resonance energy transfer) and fluorescence quenching |
| Comments |
Aptamers are artificial nucleic acid ligands, specifically generated against certain targets, such as amino acids, drugs, proteins or other molecules. A molecular beacon was first reported by Tyagi et al 1996
PMID 9630890, who defined them as “nucleic acids probes able to
undergo spontaneous conformational change, after hybridising
their complementary nucleic acid targets, translated
into a change in their fluorogenic properties”. |
| Entered by |
Uri M |
| ID |
105438 |