Range |
Table - link
|
Organism |
Bacteria Escherichia coli |
Reference |
Cho CM, Mulchandani A, Chen W. Altering the substrate specificity of organophosphorus hydrolase for enhanced hydrolysis of chlorpyrifos. Appl Environ Microbiol. 2004 Aug70(8):4681-5.PubMed ID15294802
|
Method |
Directed evolution. Researchers used two rounds of DNA shuffling and screened about
12,000 mutants to improve the hydrolytic activity of an organophosphorus hydrolase (OPH) 725-fold
toward the toxin chlorpyrifos. |
Entered by |
Uri M |
ID |
105432 |