Size of average protein

Value 467 Amino acids Range: ±29 Table - link Amino acids
Organism Budding yeast Saccharomyces cerevisiae
Reference Harrison PM, Milburn D, Zhang Z, Bertone P, Gerstein M. Identification of pseudogenes in the Drosophila melanogaster genome. Nucleic Acids Res. 2003 Feb 1 31(3):1033-7. table 1 p.1035PubMed ID12560500
Comments Value of 466 given in Lodish et al, Molecular Cell Biology 2000, 3.1 Hierarchical Structure of Proteins, 6th paragraph under heading 'The Amino Acids Composing Proteins Differ Only in Their Side Chains': "The 6225 known and predicted proteins encoded by the yeast genome have an average molecular weight (MW) of 52,728 and contain, on average, 466 amino acid residues." Value of 415 aa given in Drummond et al., 2005 PMID 16176987 p.14340 left column 2nd paragraph: "At the canonical ribosomal error rate of 5 errors per 10,000 codons translated (ref 35), ≈19% of average length yeast proteins (415 aa) contain a missense error, and these errors may cause misfolding (ref 36)." Page link - link For protein median length of 385 aa see BNID 100206.
Entered by Uri M
ID 105224