| Value |
7
min
Range: ±2 min
|
| Organism |
Budding yeast Saccharomyces cerevisiae |
| Reference |
Wang Y, Liu CL, Storey JD, Tibshirani RJ, Herschlag D, Brown PO. Precision and functional specificity in mRNA decay. Proc Natl Acad Sci U S A. 2002 Apr 30 99(9):5860-5 p.5862 right column 3rd paragraphPubMed ID11972065
|
| Method |
By using DNA microarrays, researchers precisely measured the decay of each yeast mRNA, after thermal inactivation of a temperature-sensitive RNA polymerase II. |
| Comments |
The half-lives of the 4,687 mRNAs analyzed varied widely, ranging from ~3 min to more than 90 min, with a mean of 23 min and median of 20 min. The nucleosome core is composed of four histone subunits, in equimolar proportions, assembled into an octamer (ref 29). The 4 distinguishable histone mRNAs have closely matched, rapid decay rates, with t1/2=7±2min |
| Entered by |
Uri M |
| ID |
104742 |