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Rule of thumb for time it takes a small molecule (lactate) to diffuse across the cell

Value	0.01 sec
Organism	Budding yeast Saccharomyces cerevisiae
Reference	Calculated according to yeast cell diameter. Please see Measurement Method
Method	Taking X, distance to be traveled, as 4.5µm (BNID 100 451) and D of lactate in cytoplasm of erythrocyte in rat, 210 µm^2/sec BNID 104644. According to equation of diffusion (in 3 dimensions): t diffusion=X^2/(6×D). (4.5µm)^2/1260µm^2/sec=0.016sec˜0.01sec.
Entered by	Uri M
ID	104675