Translation rate

Value 5 aa/sec
Organism Human Homo sapiens
Reference Olofsson SO, Structure and biosynthesis of apolipoprotein B. Am Heart J. 1987 Feb113(2 Pt 2):446-52.PubMed ID3812204
Primary Source K Bostrom et al, Pulse-chase studies of the synthesis and intracellular transport of apolipoprotein B-100 in Hep G2 cells,J. Biol. Chem. 1986 261: 13800-13806
Method Calculated manually: Apolipoprotein B gene sequence spans 13,689 nucleotides from the initiation to the stop codon. Thus the messenger has the capacity to code for 4563 amino acids, corresponding to a translation rate of 5 aa/sec. Translation time of 14 min measured by Pulse-chase methodology in the Hep-G2 cell (a human liver carcinoma cell line)
Entered by Uri M
ID 104598