Comments |
"The sum of proteins per cell predicted from the curated dataset is about 53 million proteins for a fast-growing haploid yeast cell, with 90% confidence limits of 30–80 million. From the local loss-rates for individual proteins
through degradation, the global loss-rate through cell
growth, and the local protein abundance data, protein
synthesis rates can be calculated for each gene. The cell-
wide sum of these rates amounts to about 13,000 (6,500–
19,500) proteins synthesised per cell per second on aver-
age throughout the cell cycle, and, if translation initiation
and termination are assumed to be loss-free processes,
there must consequently also be about 13,000 translation
initiation and translation termination events per cell per
second." See BNID 106198 |