| Range |
6-7 hours
|
| Organism |
Fruit fly Drosophila melanogaster |
| Reference |
Vazquez J, Belmont AS, Sedat JW. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol. 2001 Aug 2111(16):1227-39.PubMed ID11525737
|
| Method |
Chromosome motion was tracked in Drosophila spermatocyte nuclei by 3D fluorescence microscopy. The Lac repressor/lac operator system was used to label specific chromosomal sites in live tissues, allowing extended observation of chromatin motion in different cell cycle stages. |
| Comments |
The results indicate a high degree of chromatin motion in early spermatocyte nuclei, with a long-range diffusion coefficient of about 1 × 10^-3 µm^2/s for individual lac O sites. At this rate, a given chromatin region is expected to travel 4.6 µm in one hour and, on average, will explore the entire nucleus (approximately 11–12 µm diameter) in approximately 6–7 hr. |
| Entered by |
Uri M |
| ID |
104291 |