Relative displacement of chromatin lac sites in nucleus

Value 0.14 µm/min
Organism Chinese hamster ovary (CHO)
Reference Cheutin T, McNairn AJ, Jenuwein T, Gilbert DM, Singh PB, Misteli T. Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science. 2003 Jan 31 299(5607):721-5.PubMed ID12560555
Method To visualize HP1 in living cells, CHO cell lines stably expressing GFP-HP1alpha, -beta, or -gamma under a tetracycline-repressible promoter were established
Comments For each HP1 isoform, the relative displacement of heterochromatin domains between time points was typically about 0.14 µm per minute (Fig. 1B)
Entered by Uri M
ID 104288