Time for red blood cell to lose biconcave shape following hemolysis

Range 2-3 Days
Organism Rat Rattus norvegicus
Reference Wagner KR, Dwyer BE. Hematoma removal, heme, and heme oxygenase following hemorrhagic stroke. Ann N Y Acad Sci. 2004 Mar1012:237-51PubMed ID15105270
Primary Source Xi G, Keep RF, Hoff JT. Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J Neurosurg. 1998 Dec89(6):991-6.PubMed ID9833826
Method In this study, the authors reexamined the role of RBCs and hemoglobin in edema formation after intracerebral hemorrhage (ICH). METHODS: The experiments involved infusion of whole blood, packed RBCs, lysed RBCs, rat hemoglobin, or thrombin into the right basal ganglia of Sprague-Dawley rats.
Entered by Uri M
ID 104200