Diffusion coefficient of parvalbumin in cytoplasm

Value 37.4 µm^2/sec Range: ±8.1 µm^2/sec
Organism Frog Rana temporaria
Reference Lin PC, Kreutzer U, Jue T. Anisotropy and temperature dependence of myoglobin translational diffusion in myocardium: implication for oxygen transport and cellular architecture. Biophys J. 2007 Apr 192(7):2608-20.PubMed ID17218454
Primary Source Maughan DW, Godt RE. Parvalbumin concentration and diffusion coefficient in frog myoplasm. J Muscle Res Cell Motil. 1999 Feb20(2):199-209PubMed ID10412091
Method The concentrations and diffusivity of two isoforms of parvalbumin, IVa and IVb, were measured using quantitative SDS PAGE in single fibers from semitendinosus muscles of the frog Rana temporaria.
Comments parvalbumin diffuses out of frog skinned fibers with an isotropic, averaged diffusion coefficient of 3.74 ± 0.81 × 10^-7 cm2/s at 4°C, which is ~1/3 the solution diffusion rate
Entered by Uri M
ID 104037