| Range |
Table - link
|
| Organism |
Unspecified |
| Reference |
Nelson & Cox, Lehninger's Principles of Biochemistry 4th Edition, 2004, WH Freeman & Co, p.207, Table 6-8 |
| Primary Source |
Fersht, A. (1999) Structure and Mechanism in Protein Science, p. 166, W. H. Freeman and Company, New York. |
| Comments |
"There is an upper limit to Kcat/Km, imposed by the rate at which E and S can diffuse together in an aqueous solution. This diffusion controlled limit is 10^8 to 10^9 M^-1×s^-1, and many enzymes have a kcat/Km near this range (table 6-8) Such enzymes
are said to have achieved catalytic perfection.
Note that different values of kcat and Km can produce
the maximum ratio." |
| Entered by |
Uri M |
| ID |
103917 |