| Value |
52
min
|
| Organism |
Yeast Kluyveromyces marxianus |
| Reference |
Groeneveld P, Stouthamer AH, Westerhoff HV. Super life - how and why 'cell selection' leads to the fastest-growing eukaryote. FEBS J. 2009 Jan276(1):254-70 abstract & p.261 left column bottom paragraphPubMed ID19087200
|
| Method |
Abstract: "By applying pH-auxostat cultivation to the already fast-growing yeast Kluyveromyces marxianus for a sufficiently long time, [investigators] selected a strain with a 30% increased growth rate, its cell-cycle time decreased to 52 min, much below that reported to date for any eukaryote. The increase in growth rate was accompanied by a 40% increase in cell surface at a fairly constant cell volume." |
| Comments |
P. 261 left column bottom paragraph: "[Investigators’] observation of microbial selection using an auxostat also addressed the second issue of [their] study, i.e. whether one of the fastest-growing eukaryotes, K. marxianus, can grow even faster on defined mineral
medium. The answer would appear to be yes. The average cell-cycle time of the faster-growing population was 52 min, which is among the shortest steady-state
cell-cycle time of any eukaryotic organism on defined glucose ⁄ammonium mineral medium, and is certainly much shorter than that of the more minimalist Mycoplasma genitalium [ref 60]. Figure 1 shows that the steadystate pH-auxostat dilution rate (D) increased from one steady state to the new steady state, and lasted many generations." |
| Entered by |
Uri M |
| ID |
103707 |