| Value |
4
Orders of magnitude
|
| Organism |
bacteria |
| Reference |
Hani S. Zaher and Rachel Green, Fidelity at the Molecular Level: Lessons from Protein Synthesis. Cell Volume 136, Issue 4, 20 February 2009, Pages 746-762PubMed ID19239893
|
| Primary Source |
Zaher HS, Green R. Quality control by the ribosome following peptide bond formation. Nature. 2009 Jan 8457(7226):161-6.PubMed ID19092806
|
| Method |
a well-defined in vitro bacterial translation system |
| Comments |
When mismatches are formed in both the P- and E-sites, as might result from iterated errors caused by the initial P-site mismatch, the rates of release on sense codons are stimulated by as much as 4 orders of magnitude. |
| Entered by |
Uri M |
| ID |
103487 |