Increase in lactate dehydrogenase activity upon change of substrate

Value 3000 Fold
Organism Bacteria Geobacillus stearothermophilus
Reference Karagüler NG, Sessions RB, Binay B, Ordu EB, Clarke AR. Protein engineering applications of industrially exploitable enzymes: Geobacillus stearothermophilus LDH and Candida methylica FDH. Biochem Soc Trans. 2007 Dec35(Pt 6):1610-5.PubMed ID18031276
Comments a 3000-fold improvement on changing the substrate specificity of bsLDH from pyruvate/lactate to malate/oxaloacetate
Entered by Uri M
ID 102611