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"The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million African children annually." "The P. falciparum 3D7 nuclear genome is composed of 22.8 megabases (Mb) distributed among 14 chromosomes ranging in size from approximately 0.643 to 3.29 Mb (Fig. 1, and Supplementary Figs A–N)." "Approximately 5,300 protein-encoding genes were identified, about the same as in S. pombe (Table 1, and Supplementary Table A). This suggests an average gene density in P. falciparum of 1 gene per 4,338 base pairs (bp), slightly higher than was found previously with chromosomes 2 and 3 (1 per 4,500 bp and 1 per 4,800 bp, respectively)." Note to value of 5,268, beneath table 1:"*70% of these genes matched expressed sequence tags or encoded proteins detected by proteomics analyses [refs 14,15]" Since there are 5268 genes, there are 5268 proteins predicted. On 14 chromosomes. |