Normal doubling time in human intestinal tract

Value 40 hours
Organism Bacteria Escherichia coli
Reference Michael A. Savageau, 1983, Escherichia coli Habitats, Cell Types, and Molecular Mechanisms of Gene Control, The American Naturalist, Vol. 122, No. 6, (Dec., 1983), p.733 2nd paragraph
Primary Source Grovum, W. L., and G. D. Phillips. 1973. Rate of passage of digesta in sheep. Br. J. Nutr. 30:377-390. AND Cummings JH, Wiggins HS. Transit through the gut measured by analysis of a single stool. Gut. 1976 Mar17(3):219-23 AND Fioramonti, J., and L. Bueno. 1980. Motor activity in the large intestine of the pig related to dietary fiber and retention time. Br. J. Nutr. 43:155-162 AND Gear, J. S. S., A. J. M. Brodribb, A. Ware, and J. T. Mann. 1980. Fiber and bowel transit times. Br. J. Nutr. 45:77-82.PubMed ID4795757, 1269990, 6245676, 6258626
Method From measurements of mean transit time through the intestinal tract
Comments P.733 2nd paragraph: "From measurements of mean transit time through the intestinal tract (primary sources), one can calculate that E. coli normally grows with an average net positive rate of about one doubling every 40 h." Additional ref- link where "in the intestinal tract, the coliform's generation time is estimated to be 12-24 hours."
Entered by Uri M
ID 102096