Ratio of H+ to ATP in mitochondrial ATP synthase (including transport costs)
| Range | 13:3 H+/ATP |
|---|---|
| Organism | Generic |
| Reference | Rich, PR. The molecular machinery of Keilin's respiratory chain. Biochem Soc Trans. 2003 Dec31(Pt 6) p.1103, subheading A re-evaluation of yields of ATP synthesis from glucose oxidation.PubMed ID14641005 |
| Comments | The motor unit of ATP synthase requires 10 H+ to complete a full rotation, which results in the generation of three ATP. The transport of the ADP and phosphate into the mitochondria costs one H+, so this adds three protons for a full rotation. This value was based on the structure of the yeast ATP synthase, but should be true for other eukaryotes which have a structurally similar mitochondrial ATP synthase. |
| Entered by | Phil Mongiovi |
| ID | 101775 |