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Number of various signaling protein molecules in one cell

Range	Table - link
Organism	Various
Reference	S Legewie, H Herzel, H Westerhoff, and N Bluthgen. Recurrent design patterns in the feedback regulation of the mammalian signalling network. Molecular Systems Biology. 2008. 4:190 doi: 10.1038/msb.2008.29. Supplementary material, Heading II, pp.6-7 of 43PubMed ID18463614
Primary Source	See pointers to refs on right of table
Comments	"About 4000 genes are annotated with the term signal transduction in Ensembl. Assuming a typical signaling protein expression of 20,000 molecules per cells (see Table and (Aldridge et al, 2006. Haughet al, 2004)), this would sum up to ~4% of total protein.“About 4000 genes are annotated with the term signal transduction in Ensembl. Assuming a typical signaling protein expression of 20,000 molecules per cells (see Table and (Aldridge et al, 2006. Haughet al, 2004)), this would sum up to ~4% of total protein."
Entered by	Phil Mongiovi
ID	101729