Results
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Property | Organism | Value | Units | ID | Details |
---|---|---|---|---|---|
Potentially mutagenic lesions in DNA | Mammals | ~20,000 | lesions/diploid cell/day | 112657 | Preston BD, Albertson TM... |
Mitochondrial DNA mutation rate | Human Homo sapiens | ~2.7×10^-5 | substitutions/site/generation | 111228 | Schneider S, Excoffier... |
Mutation rate per base pair per replication | Human Homo sapiens | 5E-11 (Table - link) | Mutation/bp/replication | 105095 | Drake JW, Charlesworth B... |
Mitochondrial DNA mutation rate calibrated by the divergence between humans and chimpanzees | Human Homo sapiens | ~3×10^-6 | substitutions/site/generation of 20 years | 111227 | Schneider S, Excoffier... |
Mutation rate per base pair per generation | Fruit fly Drosophila melanogaster | 8.5E-09 | mutation/bp/generation | 106793 | Drake JW, Charlesworth B... |
Fraction of mutation events that are multi-step changes | vertebrates | 5 - 75 | % | 112165 | Ellegren H. Microsatellites:... |
Spontaneous base loss | Unspecified | ~10,000 | bases/cell/day | 113506 | Gangloff S, Arcangioli... |
Number of abasic sites (AP) lesions that persist at a steady-state level at normal physiological conditions | Mammals | 50,000 - 200,000 | lesions | 113507 | Gangloff S, Arcangioli... |
DNA–DNA surface separation | Bacteriophage Lambda | 7 | Å | 111740 | Liu T et al., Solid-... |
Mutation rate per base pair per replication (very old estimate, see below) | Bacteria Escherichia coli | 5.4E-10 (Table - link) | mutation/bp/replication | 100263 | Drake JW, A constant... |
Mutation rate (from whole-genome sequencing studies of family trios) | Human Homo sapiens | ~1×10^−8 to 1.5×10^−8 | mutations/site/generation | 112456 | Rahbari R et al., Timing... |
Average addition of de novo mutations (DNM) in the child with every additional year in father's age | Human Homo sapiens | ~2 (on average 2.9 DNM with each additional year in parents' ages) | additional mutations per paternal year | 112457 | Rahbari R et al., Timing... |
Mutation rate | Human Homo sapiens | 1.28E-08 (1.13×10^−8 to 1.43×10^−8) | mutations/site/generation | 112459 | Rahbari R et al., Timing... |
Ratio of paternal to maternal germ line mutations | Human Homo sapiens | 3.5 | unitless | 112462 | Rahbari R et al., Timing... |
DNA replication rate of DNA polymerase II (slow-dna repair) | Bacteria Escherichia coli | 20-30 | nucleotides/sec | 104125 | Bonner CA, Stukenberg PT... |
Mutation rate per genome per replication | Human Homo sapiens | 0.16 (Table - link) | mutation/genome/replication | 100417 | Drake JW, Charlesworth B... |
Ratio between mitochondrial DNA and nuclear DNA | Eukaryotes | <= (<0.01) | unitless | 102917 | Robin ED, Wong R. Mi... |
Mitochondrial DNA | African clawed frog Xenopus laevis | 1e+8 | genomes | 100326 | Gurdon and Wakefield... |
DNA packaging | Various | Cells other than in sperm nuclei, in vivo ∼5–10% viral capsids 55% | % | 111739 | Liu T et al., Solid-... |
DNA mass per double stranded DNA virus | Virus | 0.09 | fg dsDNA/virus | 105851 | Wommack KE, Colwell RR.... |