Results
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Property | Organism | Value | Units | ID | Details |
---|---|---|---|---|---|
Mutation rate per base pair per replication | Human Homo sapiens | 5E-11 (Table - link) | Mutation/bp/replication | 105095 | Drake JW, Charlesworth B... |
Mutation rate per base pair per replication (very old estimate, see below) | Bacteria Escherichia coli | 5.4E-10 (Table - link) | mutation/bp/replication | 100263 | Drake JW, A constant... |
Mutation rate per base pair per generation | Human Homo sapiens | 2.5E-08 | Mutation/bp/generation | 100414 | Nachman MW, Crowell SL.... |
Mutation rate per base pair per replication | Bacteriophages T2 and T4 | 2.4E-08 | mutation/bp/replication | 100228 | Drake JW, Charlesworth B... |
Replication errors per genome | Bacteria Escherichia coli | 2.5e-3 | Unitless | 102008 | Drake JW, A constant... |
Mutation rate per base pair per replication | Bacteriophage M13 | 7.2E-07 | mutation/bp/replication | 100224 | Drake JW, Charlesworth B... |
Mutation per base pair per generation (germline mutation) | Human Homo sapiens | 1E-08 | mutation/bp/generation | 105813 | 1000 Genomes Project... |
Effects of mutations in TEM1 (beta-lactamase) | bacteria | ~30% cause a partial reduction in fitness: ~62% have no immediate measurable effects on fitness | % of mutations | 110450 | Soskine M, Tawfik DS.... |
Mutation rate estimated using classical fluctuation tests, scoring for resistance to rifampicin (Rif R) and to nalidixic acid (Nal R) | Bacteria Escherichia coli | (Rif R) 0.33×10^−10 (Nal R) 0.21×10^−10 | mutations/nucleotide/generation | 111340 | Lee H, Popodi E, Tang H... |
Fraction of mutations that are lethal | Bacteria Escherichia coli | ~1 | % | 114862 | Lydia Robert, Jean Ollion... |
Estimates of the mutation rate per site per generation for 26 species of bacteria | bacteria | Table - link | Mutation rate(×10^-10)/site/generation | 115550 | Gibson B, Wilson DJ, Feil E... |
Rates of spontaneous mutation in DNA-based microbes | Various | Table - link | N/A | 103918 | Drake JW, A constant... |
Estimated mutation rate | RNA viruses | 10^-4 to 10^-6 | substitutions per base | 112262 | Acevedo A, Brodsky L... |
Mutation rate | Bacteria Escherichia coli | wild type ~0.0022: mutH mutant ~0.32 | mutation/hour | 114861 | Lydia Robert, Jean Ollion... |
81 estimates of the rate at which bacteria accumulate mutations per site per year (the accumulation rate) for 34 species of bacteria | bacteria | Table - link | Accumulated mutations(×10^-7)/site/year | 115549 | Gibson B, Wilson DJ, Feil E... |
Substitution rate per synonymous site | Bacteria Escherichia coli | 4.5E-09 (Table - link) | Substitutions/year | 105030 | Ochman H, Elwyn S, Moran... |
Genomic substitution rates (U) per generation | Bacteria Escherichia coli | 0.0001-0.0002 | Substitutions/generation | 105031 | Ochman H, Elwyn S, Moran... |