Lac repressor concentration

Value ~10 nM
Organism Bacteria Escherichia coli
Reference Benno Muller-hill, 1996, The Lac Operon: A Short History Of A Genetic Paradigm, Publisher: Walter de Gruyter. Berlin. New York. Part 3.2 pp.135
Primary Source Gilbert W, M¨ uller-Hill B. 1966. Isolation of the lac repressor. Proc. Natl. Acad. Sci. USA 56:1891–98PubMed ID7526223
Method Calculating according to approximately ten molecules of tetrameric lac repressor in each cell
Comments This concentration corresponds to about 10 repressors per cell (BNID 102 068). 20 monomers per lacI gene given in Elf et al, 2007, PMID 17525339. See BNID 103602 for value of 50 nM.
Entered by Uri M
ID 102083