Flap endonuclease (FEN) turnover rate

Value 37 min^-1
Organism Bacteria Escherichia coli
Reference Allen LM, Hodskinson MR, Sayers JR. Active site substitutions delineate distinct classes of eubacterial flap endonuclease. Biochem J. Biochem J. 2009 Mar 1 418(2):285-92. doi:10.1042/BJ20081637 p.289 left column 2nd paragraphPubMed ID19000038
Primary Source Setlow P, Kornberg A. Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. J Biol Chem. 1972 Jan 10 247(1):232-40.PubMed ID4552925
Comments the activity of SaFEN is approximately three-fold greater. See BNID 102586
Entered by Uri M
ID 102587